abstract：:This study was designed to evaluate the role of nitric oxide (NO) in FK506-induced nephrotoxicity by administering an inhibitor of NO synthesis, N omega-nitro-L-arginine methyl ester (L-NAME) to rats treated with FK506. After one week of treatment with FK506 (3.2 mg/kg/day, intramuscularly) and/or L-NAME (5 mg/100 mL ...

journal_title：Renal failure

authors： Wang L,Kubodera S,Ueno A,Takeda M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Despite the widespread availability of dialytic and intensive care unit technology, the probability of early mortality in critically ill patients with acute renal failure (ARF) is still high, and the evaluation of the patients' prognosis has been difficult. The Acute Physiology and Chronic Health Evaluation ...

journal_title：Renal failure

authors： Chen YC,Hsu HH,Kao KC,Fang JT,Huang CC

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Acute hyperammonemia caused by urea cycle disorder is a medical emergency for which immediate managements should be taken to minimize permanent brain damage. Among different enzyme defects, ornithine transcarbamylase deficiency (OTC) is one of the most common enzyme defect in urea cycle disorders. We utilize...

journal_title：Renal failure

authors： Chen CY,Chen YC,Fang JT,Huang CC

更新日期：2000-11-01 00:00:00

abstract：:Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...

journal_title：Renal failure

authors： Baldwin I,Tan HK,Bridge N,Bellomo R

更新日期：2000-05-01 00:00:00

abstract：:The present study was undertaken to examine the role of arachidonic acid (AA) metabolites in hypoxia/reoxygenation (H/R)-induced renal cell injury in rabbit renal cortical slices using AA metabolic inhibitors. Inhibitors of cyclooxygenase (indomethacin and diclofenac sodium) and lipoxygenase pathways (nordihydroguaiar...

journal_title：Renal failure

authors： Kim YK,Hwang MY,Woo JS,Jung JS,Lee SH

更新日期：2000-03-01 00:00:00

abstract：:Atrial Natriuretic Peptide (ANP), has protective effect on the outcome of acute renal failure in animals when infused over short periods of time. Escherichia Coli heat-stable enterotoxin (STa) acts on a particulate guanylate cyclase receptors leading to an increase in cytosolic cGMP similar to ANP. STa has longer dura...

journal_title：Renal failure

authors： Abdulla HM

更新日期：2000-01-01 00:00:00

abstract：:The aim of this investigation was to study the validity of the radionuclide methods in the estimation of kidney function, for prognosis and follow-up of acute renal failure (ARF). In thirty-one ARF patients, the evaluation of glomerular filtration rate (GFR) by 99mTc-DTPA clearance and effective renal plasma flow (ERP...

journal_title：Renal failure

authors： Ilic S,Rajic M,Vlajkovic M,Bogicevic M,Stefanovic V

更新日期：2000-01-01 00:00:00

abstract：:We studied gene expression for transforming growth factor (TGF)-alpha, epidermal growth factor (EGF), heparin binding (HB) EGF, and the EGF receptor following acute renal failure induced by mercuric chloride administration to gain insight into potential mechanisms of renal repair. Twenty four hours after HgCl2, 2 mg/k...

journal_title：Renal failure

authors： Hise MK,Liu L,Salmanullah M,Drachenberg CI,Papadimitriou JC,Rohan RM

更新日期：2000-01-01 00:00:00

abstract：:Rhabdomyolysis is common clinical and laboratory syndrome resulting from skeletal muscle injury and acute renal failure is the most important complication. Acute renal failure is common in critically ill medical patients. The aim of our study was to determine the prevalence of rhabdomyolysis induced acute renal failur...

journal_title：Renal failure

authors： Hojs R,Ekart R,Sinkovic A,Hojs-Fabjan T

更新日期：1999-11-01 00:00:00

abstract：:The effect of ticlopidine on rats with adriamycin nephropathy was observed during 26 weeks. In the ticlopidine-treated nephrotic animals (TNG), proteinuria was less than in the untreated nephrotic animals (NG), but this difference was significant only at week 6 (TNG = 47.27 +/- 16.52 versus NG = 100.08 +/- 13.83 mg/24...

journal_title：Renal failure

authors： Riyuzo MC,Soares VA

更新日期：1999-09-01 00:00:00

abstract：:Nontraumatic rhabdomyolysis is an important but under-recognized cause of acute renal failure. In alcoholics, rhabdomyolysis most frequently develop following muscle necrosis during alcohol-induced coma, but has also been described rarely in those without prolonged coma or seizures. We describe a patient who developed...

journal_title：Renal failure

authors： Muthukumar T,Jha V,Sud A,Wanchoo A,Bambery P,Sakhuja V

更新日期：1999-09-01 00:00:00

abstract：:Aquaporin-2 protein levels can be detected in the urine of normal of subjects if measured after fluid deprivation. By contrast, in patients with nephrogenic diabetes insipidus caused by mutations in the aquaporin-2 gene, urine aquaporin-2 protein excretion cannot be detected. We propose that properly standardized meas...

journal_title：Renal failure

authors： Sisson D,Batlle D

更新日期：1999-05-01 00:00:00

abstract：:The study of urinary proteins is an important tool in the screening and diagnosis of patients with renal impairment. Quantification of total proteins, although useful, can provide only limited information. Gel electrophoresis of urine samples may provide more detailed information. ...

journal_title：Renal failure

authors： Behets GJ,De Broe ME

更新日期：1999-05-01 00:00:00

abstract：:Prevention of secondary hyperparathyroidism (SHPTH) and treatment of the moderate cases by small p.os doses of Vitamin D has not been thoroughly investigated on the long term, while large doses of Vitamin D have been successful in the short term treatment of this entity. We administered calcitriol p.os 0.5-1.0 microgr...

journal_title：Renal failure

authors： Vlassopoulos D,Noussias C,Revenas K,Hadjilouka-Mantaka A,Arvanitis D,Tzortzis G,Hadjiconstantinou V

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Ularitide is a member of the natriuretic peptide family. This hormone exhibits an N-terminal extension by four amino acids compared with atrial natriuretic peptide. Ularitide was shown to exert strong diuretic and natriuretic effects when infused intravenously. Its main action sites are the glomerulum, induc...

journal_title：Renal failure

authors： Meyer M,Pfarr E,Schirmer G,Uberbacher HJ,Schöpe K,Böhm E,Flüge T,Mentz P,Scigalla P,Forssmann WG

更新日期：1999-01-01 00:00:00

abstract：:Paraproteins or monoclonal proteins are the result of clonal B-cell or plasma cell proliferation of a malignant, premalignant or non-malignant nature. Monoclonal proteins may consist of intact immunoglobulin molecules or of heavy or light chains only. Depending on their rate of production and/or secretion they may acc...

journal_title：Renal failure

authors： Maniatis A

更新日期：1998-11-01 00:00:00

abstract：:The present study was undertaken to verify the hypothesis that infusion of atrial natriuretic peptide (ANP) might lower preload and be beneficial in the treatment of pulmonary congestion even without a diuresis in patients with acute renal failure (ARF) secondary to severe congestive heart failure (CHF). We studied 22...

journal_title：Renal failure

authors： Seta K,Hayashi T,Sugawara A,Kasuno K,Watanabe S,Sumi Y,Kijima Y,Kawaguchi K,Kotake C,Seo T,Toda T,Kuwahara T

更新日期：1998-09-01 00:00:00

abstract：:The aim of the study was to determine the relationship, if any, between abnormalities in urinary cytology and the administration of cyclosporine A in bone marrow transplant recipients. Specific attention was given to the presence of tubular cells with round inclusions (TCRI). Two bone marrow transplant recipient group...

journal_title：Renal failure

authors： Sucic M,Boban D,Markovic-Glamocak M,Bogdanic V,Nemet D,Labar B,Cvoriscec D,Plavsic F,Stoos-Veic T,Mrsic M

更新日期：1998-07-01 00:00:00

abstract：:Acute renal failure (ARF) is one of the most frequent and potentially life threatening complications following bone marrow transplantation (BMT). Several renal syndromes that occur are either unique or occur with a disproportionate frequency post-BMT. Clinically ARF can be classified according to the time of onset pos...

journal_title：Renal failure

authors： Pulla B,Barri YM,Anaissie E

更新日期：1998-05-01 00:00:00

abstract：:The clinical course of 15 patients with Wegener's granulomatosis (WG) and eight patients with microscopic polyangiitis (MPA) from one nephrological clinical center is presented for the period from 1984 to 1993, when testing for antineutrophil cytoplasmic antibodies (ANCA) was gradually introduced into routine clinical...

journal_title：Renal failure

authors： Schleiffer T,Burkhard B,Klooker P,Brass H

更新日期：1998-05-01 00:00:00

abstract：:We previously described a method to measure GFR in conscious spontaneously voiding rats. This method circumvents the need for anesthesia and for bladder instrumentation. It's main principle is the correction of renal 125I-iothalamate clearance for incomplete urine collection by the ratio of plasma and renal clearance ...

journal_title：Renal failure

authors： de Vries PA,Navis G,de Jong PE,de Zeeuw D

更新日期：1998-03-01 00:00:00

abstract：:During embryonic life, renal morphogenesis is characterized by a defined period of intense cellular activity, inductive-transformation of undifferentiated cells to polarized epithelia, in-growth of capillaries into an intricate parenchymal epithelial-mesenchymal mass, and finally the maturation into an organ with dive...

journal_title：Renal failure

authors： Wallner EI,Kumar A,Carone FA,Kanwar YS

更新日期：1998-03-01 00:00:00

abstract：:The ability to predict the rate of progression of renal parenchymal disease may help in its clinical management. We undertook characterization of urinary macrophages obtained from patients with various renal diseases paying special attention to the differentiation from non-progressive to progressive renal diseases. A ...

journal_title：Renal failure

authors： Hotta O,Kitamura H,Taguma Y

更新日期：1998-03-01 00:00:00

abstract：:The single dose administration of the aminonucleoside of puromycin (PAN) induces a nephrotic syndrome in rats characterized by massive proteinuria and progressive histologic changes. This model of acute parenchymal nephritis is thought to be mediated by the renal recruitment of monocytes and macrophages. To investigat...

journal_title：Renal failure

authors： Berens KL,Verani RR,Luke DR

更新日期：1998-01-01 00:00:00

abstract：:The male spontaneously hypertensive rat (SHR), as it ages, suffers many of the renal and cardiovascular complications that are recognized in humans as risk factors for radiocontrast (RC) agent induced renal failure (RF). Knowledge of this led us to test this strain of rats as a small animal model for RC-induced renal ...

journal_title：Renal failure

authors： Duarte CG,Zhang J,Ellis S

更新日期：1997-11-01 00:00:00

abstract：:We report a case of rapidly progressive diabetic nephropathy, from little diabetic change on renal biopsy to severe, nodular, diabetic nephrosclerosis over 32 months. The patient was taking an angiotensin converting enzyme inhibitor and had a mean arterial pressure of 95 mm Hg over this time period. Her dietary protei...

journal_title：Renal failure

authors： Dillon JJ,Sedmak DD,Cosio FG

更新日期：1997-11-01 00:00:00

abstract：:This article describes several topics necessary for understanding the psychological impact of disasters. Topics discussed include characteristics of disaster that impact psychological response, stages of response, factors influencing individual and collective trauma, and important aspects of psychological intervention...

journal_title：Renal failure

authors： Flynn BW

更新日期：1997-09-01 00:00:00

abstract：:At least 372 people developed crush syndrome after they were injured by the Great Hanshin-Awaji Earthquake. Of these, 23 were transferred to Osaka City General Hospital from the disaster area. The serum creatinine kinase (CK) of each of the 23 patients exceeded 10,000 IU/L. Sixteen of these patients were treated with ...

journal_title：Renal failure

authors： Shigemoto T,Rinka H,Matsuo Y,Kaji A,Tsukioka K,Ukai T,Shimaoka H

更新日期：1997-09-01 00:00:00

abstract：:Nontraumatic rhabdomyolysis may be associated with severe metabolic disturbances. In particular, previous literature has described a 8-20% incidence of acute renal failure in rhabdomyolysis. The aim of this study was to evaluate our experience on 11 patients with acute renal failure treated by high-efficiency daily he...

journal_title：Renal failure

authors： Tozzo C,Mazzarella V,Splendiani G,Casciani CU

更新日期：1997-05-01 00:00:00

abstract：:Acute renal failure (ARF) is a frequent complication in hospitalized patients and is strongly related to increase in mortality. In order to analyze the clinical outcome and the prognostic factors in hospital-acquired ARF, a prospective study was performed. Data from 200 patients with established ARF during the period ...

journal_title：Renal failure

authors： Barretti P,Soares VA

更新日期：1997-03-01 00:00:00

abstract：:The present study was carried out to describe epidemiology and clinical pattern of acute renal failure caused by leptospirosis in Uruguay. For these purposes, all literature published in Uruguay was reviewed. Three studies were analyzed: 2 series of patients and 1 case report that summarize 26 cases. The incidence of ...

journal_title：Renal failure

authors： Lombardi R

更新日期：1997-03-01 00:00:00

abstract：:Glycine has been shown to protect against cisplatin (CP) nephrotoxicity in rats and to enhance the in vitro expression of heat-shock protein (hsp) 70 in renal epithelial cells following sublethal heat shock. We hypothesized that the protective effect of glycine against CP nephrotoxicity may be due to an up-regulation ...

journal_title：Renal failure

authors： Musio F,Carome MA,Bohen EM,Sabnis S,Yuan CM

更新日期：1997-01-01 00:00:00

abstract：:We investigated the mechanism of impaired serum opsonic activity in patients suffering from chronic renal failure (CRF). Prehemodialysis pooled serum from CRF patients was fractionated using Sephadex G-50 gel chromatography, and the effects of the obtained fractions on serum opsonic activity were examined using lumino...

journal_title：Renal failure

authors： Kikuchi T,Nigawara K,Sugawara K,Nakaji S,Abe T,Satoh H

更新日期：1997-01-01 00:00:00

abstract：:In chronic renal failure (CRF), phosphate (Pi) retention may lead to secondary hyperparathyroidism and progression to end-stage renal disease (ESRD). Dietary phosphorus restriction or phosphate binders can slow progression in experimental CRF. Conversely, diets high in phosphorus can accelerate the progression toward ...

journal_title：Renal failure

authors： Loghman-Adham M,Motock GT

更新日期：1996-11-01 00:00:00

abstract：:Eight patients aged between 5 and 26 years developed rapid deterioration of renal function and became oliguric/anuric with duration ranging from 1 to 21 days. The initial functional assessment revealed severe degree of glomerular, tubular, and vascular dysfunctions. The magnitude of renal dysfunction was quantified an...

journal_title：Renal failure

authors： Futrakul N,Pochanugool C,Sitprija V,Singkhwa V,Futrakul P,Yenrudi S,Sensirivatana R,Watana D,Poshyachinda M

更新日期：1996-07-01 00:00:00

abstract：:The aim of our study was to analyze the clinical course and outcome of acute renal failure (ARF) in patients with hemorrhagic fever with renal syndrome (HFRS). From 1983 to 1995, we treated 33 patients (27 males, 6 females) aged from 16 to 71 years. Half of patients were connected with work at a farm or in a forest. T...

journal_title：Renal failure

authors： Bren AF,Pavlovcic SK,Koselj M,Kovac J,Kandus A,Kveder R

更新日期：1996-07-01 00:00:00

abstract：:Prophylactic effects of N-benzoyl-beta-alanine (betamipron, BP), one of a series of N-acyl amino acids, were examined against cisplatin-induced nephrotoxicity. Male Wistar rats were injected i.p. with 6 mg/kg of cisplatin combined with an i.p. BP dose given at various times and various doses. Rats were sacrificed 5 da...

journal_title：Renal failure

authors： Tokunaga J,Kobayashi M,Nakamura C,Kitagawa A,Arimori K,Nakano M

更新日期：1996-03-01 00:00:00

abstract：:We evaluated the feasibility of magnetic resonance imaging (MRI) for early detection of tubular injury by monitoring changes in the apparent diffusion coefficient (ADC) of renal water in a rat model of myohemoglobinuric glycerol-induced acute renal failure (ARF). Diffusion-weighted MRI was performed concurrently with ...

journal_title：Renal failure

authors： Vexler VS,Roberts TP,Rosenau W

更新日期：1996-01-01 00:00:00

abstract：:Abnormal glucose metabolism in uremia may result from a complex interplay between decreased insulin secretion and insulin resistance. Recent studies report beneficial effect of biotin administration in glucose metabolism in diabetic animals and in a small number of patients with diabetes mellitus. The aim of the prese...

journal_title：Renal failure

authors： Koutsikos D,Fourtounas C,Kapetanaki A,Agroyannis B,Tzanatos H,Rammos G,Kopelias I,Bosiolis B,Bovoleti O,Darema M,Sallum G

更新日期：1996-01-01 00:00:00

abstract：:Experimental perfusions of isolated rat kidneys were performed with flow rates adjusted to produce comparable glomerular filtration rates (GFR) in control and experimental groups. The experimental perfusate, consisting of Krebs-Ringer bicarbonate (KRB) containing 3.5% (uncrosslinked) stroma-free hemoglobin (SFH) plus ...

journal_title：Renal failure

authors： Millis RM,Barber JD,Anderson WA,Dehkordi O

更新日期：1995-11-01 00:00:00